Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/172608
Title: | SIRT2 in age-related neurodegenerative disorders |
Author: | Fourcade, Stéphane Outeiro, Tiago F. Pujol Onofre, Aurora |
Keywords: | Malalties neurodegeneratives Envelliment Neurodegenerative Diseases Aging |
Issue Date: | 1-Mar-2018 |
Publisher: | Impact Journals Llc. |
Abstract: | Sirtuin 2 (SIRT2) is one of seven members of the NAD+-dependent histone deacetylases (HDAC) family of proteins. Sirtuins play diverse roles in cellular metabolism and the aging process. SIRT2 is located in the nucleus, cytoplasm, and mitochondria, is highly expressed in the central nervous system (CNS), and has been reported to regulate a variety of processes including oxidative stress, genome integrity, and myelination [1]. |
Note: | Reproducció del document publicat a: https://doi.org/10.18632/aging.101397 |
It is part of: | Aging-us, 2018, vol. 10, num. 3, p. 295-296 |
URI: | http://hdl.handle.net/2445/172608 |
Related resource: | https://doi.org/10.18632/aging.101397 |
Appears in Collections: | Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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File | Description | Size | Format | |
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FourcadeS.pdf | 272.21 kB | Adobe PDF | View/Open |
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