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Title: | New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The "Time-Within-Remission Range" |
Author: | Hollanda Ramírez, Ana M. de Lecube, Albert Rubio, Miguel Angel Sánchez, Enric Vilarrasa, Nuria Oliva, José Gregorio Fernández Soto, María Luisa Salas Salvadó, Jordi Ballesteros Pomar, María D. Ciudin, Andrea Torres, Ferran Vidal, Concepción Morales, María José Valdés, Sergio Pellitero, Silvia Minambres, Inka Masmiquel, Lluís Goday Arnó, Albert Suarez, Lorena Flores, Liliam Bueno, Marta Caixàs i Pedragós, Assumpta Bretón, Irene Cámara, Rosa Olbeyra, Romina Penso, Rona Cruz, María José de la Simó Servat, Andreu Pereyra García, Francisca María López Mezquita, Elena Teresa Gils, Anna Fidilio, Enzamaria Bandrés, Orosia Martínez, Ángel Abuín, Jose Marques Pamies, Montserrat Tuneu, Laura Arteaga, Magdalena Castañer, Olga Goni, Fernando Arrizabalaga, Cristina Botana, Manuel Antonio Calanas, Alfonso Rebollo, Ángel |
Keywords: | Diabetis Cirurgia de l'obesitat Diabetes Obesity surgery |
Issue Date: | 1-Apr-2020 |
Publisher: | MDPI |
Abstract: | Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery or are unable to sustain this effect long term. Our objective was to delve further into the dynamic responses of diabetes after bariatric surgery and to evaluate the "time-within-remission range" as a variable of metabolic control. A descriptive cohort study was done using a computerised multicentre and multidisciplinary registry. All data were adjusted by propensity score. A total of 1186 subjects with a follow-up of 4.5 +/- 2.5 years were included. Type of surgery, diabetes remission, recurrence of diabetes, "time-within-remission range" and key predictors of diabetes outcomes were assessed. All patients (70% women, 51.4 +/- 9.2 years old, body mass index (BMI) 46.3 +/- 6.9 kg/m(2)) underwent primary bariatric procedures. "Time-within-remission range" were 83.3% (33.3-91.6) after gastric bypass, 68.7% (7.1-87.5) after sleeve gastrectomy and 90% (83.3-92.8) after malabsorptive techniques (p < 0.001 for all). Duration of diabetes, baseline HbA1c and insulin treatment were significantly negatively correlated with the "time-within-remission range". The association of bariatric techniques with "time-within-remission range", using gastric bypass as a reference, were: odds ratio (OR) 3.70 (2.34-5.84), p < 0.001 for malabsorptive techniques and OR 0.55 (0.40-0.75), p < 0.001 for sleeve gastrectomy. Characteristics of type 2 diabetes powerfully influence the outcomes of bariatric surgery. The "time-within-remission range" unveils a superiority of gastric bypass compared to sleeve gastrectomy. |
Note: | Reproducció del document publicat a: https://doi.org/10.3390/jcm9041070 |
It is part of: | Journal of Clinical Medicine, 2020, vol. 9, num. 4 |
URI: | http://hdl.handle.net/2445/173083 |
Related resource: | https://doi.org/10.3390/jcm9041070 |
Appears in Collections: | Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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