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http://hdl.handle.net/2445/175985
Title: | Long-term clinical and functional course of Borderline Personality Disorder: A meta-analysis of prospective studies |
Author: | Álvarez Tomás, Irene Ruiz Rodríguez, José Guilera Ferré, Georgina Bados López, Arturo |
Keywords: | Trastorns límits de la personalitat Metaanàlisi Borderline personality disorder Meta-analysis |
Issue Date: | Feb-2019 |
Publisher: | Cambridge University Press |
Abstract: | Background: This meta-analytic review is the first to synthesize findings from prospective research on the long-term course of borderline personality disorder in adult clinical populations. Methods: Systematic searches were conducted in Medline, PsycINFO, PsycArticles, PubMed, and Scopus within the period 1990-2017. Inclusion criteria were: (1) adult BPD sample diagnosed by a validated, semi-structured interview; (2) at least two prospective assessments of outcomes; and (3) follow-up period ≥ 5 years. Quality of evidence was rated with the Systematic Assessment of Quality in Observational Research (SAQOR). Four outcomes were meta-analysed using mixed-effect methods: remission from BPD diagnosis, completed suicide, depressive symptoms, and functioning. Potential moderators regarding the natural course and the initial treatment received were studied. Results: Eleven studies met the inclusion criteria, with 837 participants from nine countries being followed. Between 50% and 70% of the BPD patients achieved remission in the long-term. Significant reductions in depression and functional impairment were also found. Mean suicide rate ranged from 2% to 5%. Younger age was associated with a higher likelihood of remission. Being female was correlated with lower functional improvement. Despite some positive trends, there were no significant associations between treatment moderators and the long-term outcome. Conclusions: Findings suggest that the course of BPD is characterized by symptomatic amelioration and a slight functional improvement in the long-term. Age and gender modulate the long-term prognosis and should be considered to adapt treatment resources. Further research is required to draw robust conclusions on the long-term effects of psychotherapeutic interventions. |
Note: | Reproducció del document publicat a: https://doi.org/10.1016/j.eurpsy.2018.10.010 |
It is part of: | European Psychiatry, 2019, vol. 56, num. 1, p. 75-83 |
URI: | http://hdl.handle.net/2445/175985 |
Related resource: | https://doi.org/10.1016/j.eurpsy.2018.10.010 |
ISSN: | 0924-9338 |
Appears in Collections: | Articles publicats en revistes (Psicologia Social i Psicologia Quantitativa) Articles publicats en revistes (Psicologia Clínica i Psicobiologia) |
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