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cc-by (c) Artzi-Medvedik, Rada et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/199405

Quality of life and kidney function in older adults: prospective data of the SCOPE study

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Abstract: A longitudinal alteration in health-related quality of life (HRQoL) over a two-year period and its association with early-stage chronic kidney disease (CKD) progression was investigated among 1748 older adults (>75 years). HRQoL was measured by the Euro-Quality of Life Visual Analog Scale (EQ-VAS) at baseline and at one and two years after recruitment. A full comprehensive geriatric assessment was performed, including sociodemographic and clinical characteristics, the Geriatric Depression Scale-Short Form (GDS-SF), Short Physical Performance Ba􀁀ery (SPPB), and estimated glomerular filtration rate (eGFR). The association between EQ-VAS decline and covariates was investigated by multivariable analyses. A total of 41% of the participants showed EQ-VAS decline, and 16.3% showed kidney function decline over the two-year follow-up period. Participants with EQ-VAS decline showed an increase in GDS-SF scores and a greater decline in SPPB scores. The logistic regression analyses showed no contribution of a decrease in kidney function on EQVAS decline in the early stages of CKD. However, older adults with a greater GDS-SF score were more likely to present EQ-VAS decline over time, whereas an increase in the SPPB scores was associated with less EQ-VAS decline. This finding should be considered in clinical practice and when HRQoL is used to evaluate health interventions among older adults.

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ARTZI-MEDVEDIK, Rada, KOB, Robert, DI ROSA, Mirko, LATTANZIO, Fabrizia, CORSONELLO, Andrea, YEHOSHUA, Ilian, ROLLER-WIRNSBERGER, Regina, WIRNSBERGER, Gerhard, MATTACE-RASO, Francesco, TAP, Lisanne, GIL, Pedro, FORMIGA PÉREZ, Francesc, MORENO-GONZALEZ, Rafael, KOSTKA, Tomasz, GULIGOWSKA, Agnieszka, ÄRNLÖV, Johan, CARLSSON, Axel c., FREIBERGER, Ellen, MELZER, Itshak. Quality of life and kidney function in older adults: prospective data of the SCOPE study. _Journal of Clinical Medicine_. 2023. Vol. 12. [consulta: 23 de gener de 2026]. ISSN: 2077-0383. [Disponible a: https://hdl.handle.net/2445/199405]

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