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Article

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Published version

Publication date

2023-02-14

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cc-by (c) Sancho-Balsells A. et al., 2023
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/207574

Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons.

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Related resource

https://doi.org/10.3390/ijms24043833

Abstract

We found that specific manipulation of superficial but not deep pyramidal neurons of the CA1 resulted in the amelioration of depressive-like behaviors and the restoration of cognitive impairments induced by chronic stress. In summary, Egr1 might be a core molecule driving the activation/deactivation of hippocampal neuronal subpopulations underlying stress-induced alterations involving emotional and cognitive sequels.

Subject

Hipocamp (Cervell), Neurones, Memòria, Esquizofrènia, Depressió psíquica, Estrès (Psicologia)

Subject (English)

Hippocampus (Brain), Neurons, Memory, Schizophrenia, Mental depression, Stress (Psychology)

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Articles publicats en revistes (Biomedicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

SANCHO BALSELLS, Anna, et al. Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons. International Journal of Molecular Sciences. 2023. Vol. 24, num. 4. ISSN 1661-6596. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/207574

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