Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons.

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dc.contributor.authorSancho Balsells, Anna
dc.contributor.authorBorràs Pernas, Sara
dc.contributor.authorBrito, Verónica
dc.contributor.authorAlberch i Vié, Jordi, 1959-
dc.contributor.authorGirault, Jean-Antoine
dc.contributor.authorGiralt Torroella, Albert
dc.date.accessioned2024-02-15T15:23:32Z
dc.date.available2024-02-15T15:23:32Z
dc.date.issued2023-02-14
dc.date.updated2024-02-15T15:23:32Z
dc.description.abstractWe found that specific manipulation of superficial but not deep pyramidal neurons of the CA1 resulted in the amelioration of depressive-like behaviors and the restoration of cognitive impairments induced by chronic stress. In summary, Egr1 might be a core molecule driving the activation/deactivation of hippocampal neuronal subpopulations underlying stress-induced alterations involving emotional and cognitive sequels.
dc.format.extent21 p.
dc.format.mimetypeapplication/pdf
dc.identifier.doi10.3390/ijms24043833
dc.identifier.idgrec742181
dc.identifier.issn1661-6596
dc.identifier.pmid36835243
dc.identifier.urihttps://hdl.handle.net/2445/207574
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ijms24043833
dc.relation.ispartofInternational Journal of Molecular Sciences, 2023, vol. 24, num.4
dc.relation.urihttps://doi.org/10.3390/ijms24043833
dc.rightscc-by (c) Sancho-Balsells A. et al., 2023
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Biomedicina)
dc.subject.classificationHipocamp (Cervell)
dc.subject.classificationNeurones
dc.subject.classificationMemòria
dc.subject.classificationEsquizofrènia
dc.subject.classificationDepressió psíquica
dc.subject.classificationEstrès (Psicologia)
dc.subject.otherHippocampus (Brain)
dc.subject.otherNeurons
dc.subject.otherMemory
dc.subject.otherSchizophrenia
dc.subject.otherMental depression
dc.subject.otherStress (Psychology)
dc.titleCognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons.
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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