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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/27782
Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study
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Background: Characterizing and comparing the determinant of cotinine concentrations in different populations should facilitate a better understanding of smoking patterns and addiction. This study describes and characterizes determinants of salivary cotinine concentration in a sample of Spanish adult daily smoker men and women. Methods: A cross-sectional study was carried out between March 2004 and December 2005 in a representative sample of 1245 people from the general population of Barcelona, Spain. A standard questionnaire was used to gather information on active tobacco smoking and passive exposure, and a saliva specimen was obtained to determine salivary cotinine concentration. Two hundred and eleven adult smokers (>16 years old) with complete data were included in the analysis. Determinants of cotinine concentrations were assessed using linear regression models. Results: Salivary cotinine concentration was associated with the reported number of cigarettes smoked in the previous 24 hours (R2 = 0.339; p < 0.05). The inclusion of a quadratic component for number of cigarettes smoked in the regression analyses resulted in an improvement of the fit (R2 = 0.386; p < 0.05). Cotinine concentration differed significantly by sex, with men having higher levels. Conclusion: This study shows that salivary cotinine concentration is significantly associated with the number of cigarettes smoked and sex, but not with other smoking-related variables.
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FU BALBOA, Marcela, et al. Salivary cotinine concentrations in daily smokers in Barcelona, Spain: a cross-sectional study. Bmc Public Health. 2009. Vol. 9, num. 320. ISSN 1471-2458. [consulted: 19 of August of 2026]. Available at: https://hdl.handle.net/2445/27782