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jcm-14-01852-v2.pdf (2.24 MB)

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2025-03-10

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cc-by (c) Aranda et al., 2025
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/222092

Long COVID in ARDS Survivors: Insights from a Two-Year-Follow-Up Study After the First Wave of the Pandemic

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https://doi.org/10.3390/jcm14061852

Abstract

Objectives: To compare the health status, exercise capacity, and health-related quality of life (HRQoL) in survivors of COVID-19-associated acute respiratory distress syndrome (ARDS) at 8, 12, and 24 months post-diagnosis. Methods: We conducted a prospective, single-center follow-up study embedded within a larger multicenter cohort of adults with COVID-19 who required hospital admission. Eligible participants underwent clinical interviews, physical examinations, chest radiography, and the 6-min walk test (6MWT). Standardized scales were used to assess post-traumatic stress disorder (PTSD), anxiety, depression, and HRQoL. Results: Out of 1295 patients with COVID-19, 365 developed ARDS, of whom 166 survived. After excluding deaths and loss to follow-up, 95 patients were monitored for 24 months. Over 60% of patients had persistent symptoms, though significant improvements were recorded in quality of life and physical recovery. More than 70% recovered their previous physical capacity, but 15% did not return to their usual lifestyle habits. Symptoms such as arthralgia and fatigue decreased, but cognitive issues, such as memory loss and insomnia, persisted. Radiological improvements were noted, although pulmonary function remained impaired. The prevalence of PTSD and anxiety decreased, while depression remained stable at around 30%. Conclusions: Long COVID continues to impose significant physical, mental, and social challenges. Symptoms like fatigue and anxiety have a profound impact on daily life. Strategies are urgently needed to help patients regain health and resume their normal lives.

Subject

COVID-19, Pandèmia de COVID-19, 2020-2023, Síndrome del destret respiratori de l'adult

Subject (English)

COVID-19, COVID-19 Pandemic, 2020- 2023, Adult respiratory distress syndrome

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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ARANDA LOBO, Judit, et al. Long COVID in ARDS Survivors: Insights from a Two-Year-Follow-Up Study After the First Wave of the Pandemic. Journal of Clinical Medicine. 2025. Vol. 14, num. 6, pags. 1852. ISSN 2077-0383. [consulted: 7 of August of 2026]. Available at: https://hdl.handle.net/2445/222092

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