Methylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas

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dc.contributor.authorGallardo, F. (Fernando)
dc.contributor.authorEsteller, Manel
dc.contributor.authorPujol, Ramon M.
dc.contributor.authorCosta, Carlota
dc.contributor.authorEstrach Panella, Ma. Teresa (María Teresa)
dc.contributor.authorServitje Bedate, Octavio
dc.date.accessioned2020-12-14T15:49:58Z
dc.date.available2020-12-14T15:49:58Z
dc.date.issued2004-11-01
dc.date.updated2020-12-14T15:49:58Z
dc.description.abstractp15(INK4b), p16(INK4a) and O(6)-methylguanine DNA methyltransferase (MGMT) gene hypermethylation was studied in 22 patients with primary cutaneous T-cell lymphomas (CTCL). p15(INK4b) and p16(INK4a) inactivation is present in early and advanced disease and seems to be independent of disease stage. MGMT inactivation may play a pathogenetic role in a subset of CTCL.
dc.format.extent3 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec521069
dc.identifier.issn0390-6078
dc.identifier.pmid15531468
dc.identifier.urihttps://hdl.handle.net/2445/172734
dc.language.isoeng
dc.publisherFerrata Storti Foundation
dc.relation.isformatofReproducció del document publicat a: https://haematologica.org/issue/view/124
dc.relation.ispartofHaematologica, 2004, vol. 89, num. 11, p. 1401-1403
dc.rights(c) Ferrata Storti Foundation, 2004
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Ciències Clíniques)
dc.subject.classificationGenètica
dc.subject.classificationLimfomes
dc.subject.classificationCèl·lules T
dc.subject.otherGenetics
dc.subject.otherLymphomas
dc.subject.otherT cells
dc.titleMethylation status of the p15, p16 and MGMT promoter genes in primary cutaneous T-cell lymphomas
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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