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cc-by-nc (c) American Chemical Society , 2015
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/69303

Rhodium-Catalyzed Pauson−Khand Reaction Using a Small-Bite-Angle P‑Stereogenic C1‑Diphosphine Ligand

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The asymmetric Pauson−Khand reaction catalyzed by [Rh(COD)(MaxPHOS)]BF4 is described. Several 1,6-enynes have been chosen as model substrates affording moderate yields and selectivities of up to 86% ee. Besides binap-type ligands, we have demonstrated that the Pstereogenic C1-symmetry small-bite-angle ligand MaxPHOS is a viable ligand in this process. The formation of [2+2+2] cycloaddition compounds has shown to be a competitive process. A mechanism is proposed to account for the observed results. The intermediate rhodium dicarbonyl complex 6 was synthesized, and its solid-state structure was elucidated by X-ray crystallography.

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CRISTÓBAL LECINA, Edgar, et al. Rhodium-Catalyzed Pauson−Khand Reaction Using a Small-Bite-Angle P‑Stereogenic C1‑Diphosphine Ligand. Organometallics. 2015. Vol. 34, num. 20, pags. 4989-4993. ISSN 0276-7333. [consulted: 13 of June of 2026]. Available at: https://hdl.handle.net/2445/69303

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