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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/118363

Authentication of gold nanoparticle encoded pharmaceutical tablets using polarimetric signatures

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The counterfeiting of pharmaceutical products represents concerns for both industry and the safety of the general public. Falsification produces losses to companies and poses health risks for patients. In order to detect fake pharmaceutical tablets, we propose producing film-coated tablets with gold nanoparticle encoding. These coated tablets contain unique polarimetric signatures. We present experiments to show that ellipsometric optical techniques, in combination with machine learning algorithms, can be used to distinguish genuine and fake samples. To the best of our knowledge, this is the first report using gold nanoparticles encoded with optical polarimetric classifiers to prevent the counterfeiting of pharmaceutical products.

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CARNICER GONZÁLEZ, Arturo, et al. Authentication of gold nanoparticle encoded pharmaceutical tablets using polarimetric signatures. Optics Letters. 2016. Vol. 41, num. 19, pags. 4507-4510. ISSN 0146-9592. [consulted: 6 of June of 2026]. Available at: https://hdl.handle.net/2445/118363

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