Miniatura

Fitxers

678609.pdf (373.19 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2017-07-25

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/123209

EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1136/annrheumdis-2016-209770

Resum

OBJECTIVES: Develop recommendations for women's health issues and family planning in systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS). METHODS: Systematic review of evidence followed by modified Delphi method to compile questions, elicit expert opinions and reach consensus. RESULTS: Family planning should be discussed as early as possible after diagnosis. Most women can have successful pregnancies and measures can be taken to reduce the risks of adverse maternal or fetal outcomes. Risk stratification includes disease activity, autoantibody profile, previous vascular and pregnancy morbidity, hypertension and the use of drugs (emphasis on benefits from hydroxychloroquine and antiplatelets/anticoagulants). Hormonal contraception and menopause replacement therapy can be used in patients with stable/inactive disease and low risk of thrombosis. Fertility preservation with gonadotropin-releasing hormone analogues should be considered prior to the use of alkylating agents. Assisted reproduction techniques can be safely used in patients with stable/inactive disease; patients with positive antiphospholipid antibodies/APS should receive anticoagulation and/or low-dose aspirin. Assessment of disease activity, renal function and serological markers is important for diagnosing disease flares and monitoring for obstetrical adverse outcomes. Fetal monitoring includes Doppler ultrasonography and fetal biometry, particularly in the third trimester, to screen for placental insufficiency and small for gestational age fetuses. Screening for gynaecological malignancies is similar to the general population, with increased vigilance for cervical premalignant lesions if exposed to immunosuppressive drugs. Human papillomavirus immunisation can be used in women with stable/inactive disease. CONCLUSIONS: Recommendations for women's health issues in SLE and/or APS were developed using an evidence-based approach followed by expert consensus.

Matèries

Lupus eritematós, Síndrome antifosfolipídica, Embaràs, Part, Menopausa

Matèries (anglès)

Lupus erythematosus, Antiphospholipid syndrome, Pregnancy, Parturition, Menopause

Citació

Col·leccions

Articles publicats en revistes (Medicina)

Citació

ANDREOLI, L., BERTSIAS, George, AGMON-LEVIN, Nancy, BROWN, S., CERVERA I SEGURA, Ricard, COSTEDOAT-CHALUMEAU, Nathalie, DORIA, Andrea, FISCHER-BETZ, Rebecca, FORGER, F., MORAES-FONTES, M.f., KHAMASHTA, Munther a., KING, J., LOJACONO, A., MARCHIORI, F., MERONI, Pierluigi, MOSCA, Marta, MOTTA, M., OSTENSEN, M., PAMFIL, C., RAIO, L., SCHNEIDER, Matthias, SVENUNGSSON, E., TEKTONIDOU, Maria, YAVUZ, S., BOUMPAS, Dimitrios, TINCANI, Angela. EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.. _Annals of the Rheumatic Diseases_. 2017. Vol. 76, núm. 3, pàgs. 476-485. [consulta: 24 de gener de 2026]. ISSN: 0003-4967. [Disponible a: https://hdl.handle.net/2445/123209]

Exportar metadades

JSON - METS

Compartir registre