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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/207810
American Heart Association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort
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Background and aims: The American Heart Association proposed 7 ideal cardiovascular health metrics (Life's Simple 7 [LS7]) namely, not smoking, body mass index <25 kg/m2, healthy diet, moderate physical activity ≥150 min/week, total blood cholesterol <200 mg/dL, blood pressure <120/80 mmHg and fasting blood glucose <100 mg/dL. Our objective was to assess the association between these LS7 metrics and the incidence of atrial fibrillation (AF).Methods and results: A total of 6,479 participants of the PREDIMED study were included. We calculated the participants' baseline LS7 index ranging 0-7 points to categorize them according to their adherence to these LS7 health metrics. Multivariable Cox regression models were used to estimate Hazard Ratios (HR) and their 95% Confidence Intervals (95% CI). After a median follow-up of 4.8 years, we identified 250 incident cases of AF. After adjusting for potential confounders, adherence to LS7 index was not associated with the incidence of AF (adjusted HR 0.90 [95% CI: 0.56-1.45] for highest vs. lowest LS7 categories). Body mass index <25 kg/m2 was the only health metric individually associated with a lower risk of AF (HR 0.36 [95% CI: 0.16-0.78]). Conclusions: In a high cardiovascular risk Spanish population, adherence to American Heart Association's LS7 metrics was not associated with the risk of incident AF.
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DÍAZ-GUTIÉRREZ, Jesús, MARTÍNEZ-GONZÁLEZ, Miguel ángel, ALONSO, Alvaro, TOLEDO ATUCHA, Estefanía, SALAS SALVADÓ, Jordi, SORLÍ, José v., ROS RAHOLA, Emilio, FITÓ COLOMER, Montserrat, ESTRUCH RIBA, Ramon, ARÓS, Fernando, FIOL SALA, Miguel, LAPETRA, José, GOMEZ-GRACIA, Enrique, SERRA MAJEM, Lluís, PINTÓ SALA, Xavier, PORTOLES, Olga, BABIO, Nancy, CASTAÑER, Olga, RUIZ CANELA, Miguel. American Heart Association's life simple 7 and the risk of atrial fibrillation in the PREDIMED study cohort. _Nutrition Metabolism and Cardiovascular Diseases_. 2023. Vol. 33, núm. 6, pàgs. 1144-1148. [consulta: 22 de gener de 2026]. ISSN: 0939-4753. [Disponible a: https://hdl.handle.net/2445/207810]