Miniatura

Fitxers

1-s2.0-S1600613525000371-main.pdf (954.06 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2025-01-28

Llicència de publicació

cc by-nc-nd (c) Moreso, Francesc et al., 2025
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/221932

Development and validation of the Neuro-Score: a specific scale to detect and monitor cognitive impairment in kidney or liver transplant recipients

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1016/j.ajt.2025.01.031

Resum

We created and validated the Neuro-Score, a specific scale to detect and monitor cognitive impairment, including mild stages, in kidney or liver transplant recipients. A qualitative study was conducted to define a preliminary set of 62 items. Item reduction was performed using exploratory factor analysis. Confirmatory factor analysis assessed the adequacy of the factorial solution. The total scores of the Neuro-Score and mini-mental state examination were compared. Responsiveness to change was evaluated from visit 1 (baseline) to 2A (18 months later) and temporal stability from visit 2A to 2B (1-2 weeks later). Factor analysis showed 11 factors with an eigenvalue of >1. Confirmatory factor analysis yielded a logical solution with 1 factor and 11 items that explained 27.9% of the variance. The final model showed satisfactory internal consistency (Cronbach alpha- 0.82). A weak negative correlation was found between Neuro-Score and mini-mental state examination total scores (Pearson r--0.12; P-.0095). The Neuro-Score responsiveness to change was demonstrated (P-.022). No significant differences in the total score were observed between visits 2A and 2B, supporting the Neuro-Score temporal stability. The Neuro-Score scale is a simple, reliable, self-administered, easy-to-interpret, and consistent 11-item scale to detect and monitor cognitive impairment in kidney and liver transplant recipients.

Matèries

Trastorns de la cognició, Trasplantament renal, Trasplantament hepàtic

Matèries (anglès)

Cognition disorders, Kidney transplantation

Citació

Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

MORESO, Francesc, ANTONIO PONS MIÑANO, José, SÁNCHEZ FRUCTUOSO, Ana, JACAS, Carlos, ALEGRET, Montserrat, FERRER, Montserrat, COLMENERO, Jordi, ANDRÉS BELMONTE, Amado, LÓPEZ JIMÉNEZ, Verónica, PASCUAL, Sonia, MAZUECOS BLANCA, Auxiliadora, VENTURA GALIANO, Ana paz, CACHERO, Alba, RIVERO, Antonio, CRESPO, Marta, CUADRADO, Antonio, CABALLERO MARCOS, Arantxa, GONZALEZ DIÉGUEZ, Maria luisa, ALMOHALLA ALVAREZ, Carolina, MARURI KAREAGA, Naroa, ALAMO MARTINEZ, Jose m., PAGANO, Giulia, NUÑO SANTANA, Enriqueta, TORRES, Irina b., PÉREZ FLORES, Isabel, ALONSO TITOS, Juana, RODRÍGUEZ SOLER, María, MARTINEZ ALARCÓN, Laura, GARCÍA ÁLVAREZ, Teresa maría, BENEYTO CASTELLÓ, Isabel, GONZALEZ VILATARSANA, Emma, MIRAS, Francesc, GÓMEZ BRAVO, Miguel ángel. Development and validation of the Neuro-Score: a specific scale to detect and monitor cognitive impairment in kidney or liver transplant recipients. _American Journal of Transplantation_. 2025. Vol. 25, núm. 5, pàgs. 1059-1069. [consulta: 28 de gener de 2026]. ISSN: 1600-6143. [Disponible a: https://hdl.handle.net/2445/221932]

Exportar metadades

JSON - METS

Compartir registre