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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/116702
The effectiveness of influenza vaccination in the elderly in Spain in two influenza seasons: a multicenter case-control study
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Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22-47). VE was 51% (95% CI: 15-71) in patients without high-risk medical conditions and 30% (95% CI: 14-44) in patients with them. VE was 39% (95% CI: 20-53) in patients aged 65-79 years and 34% (95% CI: 11-51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.
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DOMÍNGUEZ GARCÍA, Àngela, SOLDEVILA, Núria, TOLEDO ZAVALETA, Diana isabel, GODOY I GARCÍA, Pere, ESPEJO, Elena, FERNÁNDEZ, M.a., MAYORAL, José maría, CASTILLA, Jesús, EGURROLA, Mikel, TAMAMES, Sonia, ASTRAY, Jenaro, MORALES SUÁREZ-VARELA, María, TORNER GRÀCIA, Núria. The effectiveness of influenza vaccination in the elderly in Spain in two influenza seasons: a multicenter case-control study. _Eurosurveillance_. 2017. Vol. 22, núm. 34, pàgs. 30602. [consulta: 27 de gener de 2026]. ISSN: 1560-7917. [Disponible a: https://hdl.handle.net/2445/116702]