Miniatura

Fitxers

680643.pdf (616.73 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2017-11-14

Llicència de publicació

cc-by (c) Garriga, César et al., 2017
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/130985

Evolution of acute hepatitis C virus infection in a large European city: Trends and new patterns.

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1371/journal.pone.0187893

Resum

The aims of this study were to describe the evolution of acute hepatitis C virus (HCV) infections since 2004 and to determine its associated factors. Acute HCV infections diagnosed in Barcelona from 2004 to 2015 were included. Incidence ratios (IR) were then estimated for sex and age groups. Cases were grouped between 2004-2005, 2006-2011 and 2012-2015, and their incidence rate ratios (IRR) were calculated. In addition, risk factors for acute HCV infection were identified using multinomial logistic regression for complete, available and multiple imputed data. 204 new HCV cases were identified. Two peaks of higher IR of acute HCV infection in 2005 and 2013 were observed. Men and those aged 35-54 had higher IR. IRR for men was 2.9 times greater than in women (95% confidence intervals (CI): 1.8 ‒ 4.7). Factors related to the period 2012-2015 (versus 2006-2011) were: a) sexual risk factor for transmission versus nosocomial (relative-risk ratio (RRR): 13.0; 95% CI: 2.3 ‒ 72.1), b) higher educated versus lower (RRR: 5.4; 95% CI: 1.6 ‒ 18.7), and c) HIV co-infected versus not HIV-infected (RRR: 53.1; 95% CI: 5.7 ‒ 492.6). This is one of the few studies showing IR and RRRs of acute HCV infections and the first focused on a large city in Spain. Sexual risk for transmission between men, higher educational level and HIV co-infection are important factors for understanding current HCV epidemic. There has been a partial shift in the pattern of the risk factor for transmission from nosocomial to sexual.

Matèries

Virus de l'hepatitis C, Infeccions per VIH, Malalties de transmissió sexual, Barcelona (Catalunya)

Matèries (anglès)

Hepatitis C virus, HIV infections, Sexually transmitted diseases, Barcelona (Catalonia)

Citació

Col·leccions

Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

GARRIGA, César, MANZANARES LAYA, Sandra, GARCÍA DE OLALLA, Patricia, GORRINDO, Pilar, LENS GARCÍA, Sabela, SOLÀ, Ricard, MARTÍNEZ REBOLLAR, María, LAGUNO CENTENO, Montserrat, NAVARRO, Jordi, TORRAS, Xavier, GURGUÍ, Mercè, BARBERÁ, Maria jesús, QUER, Josep, MASDEU, Eva, SIMÓN, Pere, ROS, Miriam, ANDRÉS, Ana de, CAYLÀ I BUQUERAS, Joan a.. Evolution of acute hepatitis C virus infection in a large European city: Trends and new patterns.. _PLoS One_. 2017. Vol. 12, núm. 11, pàgs. e0187893. [consulta: 28 de gener de 2026]. ISSN: 1932-6203. [Disponible a: https://hdl.handle.net/2445/130985]

Exportar metadades

JSON - METS

Compartir registre