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Fitxers

prosthesis-07-00002.pdf (734.88 KB)

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Data de publicació

2024-12-28

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cc-by (c) Pérez Muñoz, Israel et al., 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/221275

Spanish Multicenter Megaprosthesis Study (MEGAPROT) on 816 Tumor Prostheses: Main Results

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Recurs relacionat

https://doi.org/10.3390/prosthesis7010002

Resum

(1) Background: The use of tumor megaprostheses faces challenges, but the published series are typically small and offer limited solutions. Our aim was to compile a large series; describe patient profiles and surgical techniques; analyze prosthetic survival identifying factors affecting survival; and provide a basis for future subanalyses. (2) Methods: This is a retrospective observational multicenter study that included patients with a tumor megaprosthesis in any anatomical location. Demographic, etiologic, and surgical variables were analyzed. Data on complications and survival were also collected. (3) Results: Our series includes a total of 816 prostheses (585 primary, 181 revision, and 50 second revision). The patients' mean age was 44.2 +/- 20.8 years. Primary surgeries were performed on the femur (n = 404; 69.1%), tibia (n = 79; 13.5%), humerus (n = 74; 12.6%), pelvis (n = 20; 3.4%), and scapula (n = 4; 0.7%). Survival following primary surgery was 73.3% at 10 years. No statistically significant differences were found with respect to survival from primary surgery between males and females (p = 0.194), between the different etiologies (p = 0.540), or between the lower and the upper limb (p = 0.618). In contrast, statistically significant survival differences were found when the type of fixation was analyzed (p < 0.001). (4) Conclusions: This study analyzed one of the largest series of patients treated with tumor megaprostheses, demonstrating their acceptable survival and validating them as a treatment option for bone tumors.

Matèries

Pròtesis, Tumors

Matèries (anglès)

Prosthesis, Tumors

Citació

Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

PÉREZ MUÑOZ, Israel, et al. Spanish Multicenter Megaprosthesis Study (MEGAPROT) on 816 Tumor Prostheses: Main Results. Prosthesis. 2024. Vol. 7, num. 1. ISSN 2673-1592. [consulted: 15 of August of 2026]. Available at: https://hdl.handle.net/2445/221275

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