Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

Files

bassat2016_2157.pdf (812.04 KB)

Document type

Article

Version

Accepted version

Publication date

2016-07-11

All rights reserved

Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/100564

Hypoxaemia in Mozambican children < 5 years of age admitted to hospital with clinical severe pneumonia: clinical features and performance of predictor models

Journal Title

Authors

Director/Tutor

Journal ISSN

Volume Title

Related resource

http://dx.doi.org/10.1111/tmi.12738

Abstract

OBJECTIVE: To determine the prevalence of hypoxaemia among under-five children admitted to hospital with clinical severe pneumonia, and to assess the performance to diagnose hypoxaemia of models based on clinical signs. METHODS: We conducted a hospital-based survey in a district hospital from Southern Mozambique. RESULTS: A total of 825 children were recruited after obtaining an informed consent. The prevalence of hypoxaemia on admission was 27.9%, and 19.8% of these children died (OR compared to non-hypoxaemic children 3.22, 95%CI 1.98 - 5.21, p<0.001). The model with larger area under the ROC curve (AUC-ROC) to predict hypoxaemia included cyanosis or thoracoabdominal breathing or respiratory rate >/= 70 breaths per minute. None of the models performed well when tested in different case scenarios of oxygen availability through mathematical modelling, with over 50% of hypoxaemic children not receiving oxygen even in favourable case scenarios. CONCLUSIONS: Clinical signs alone or in combination are not suitable to diagnose hypoxaemia. The use of pulse oximeters should be strongly encouraged. This article is protected by copyright. All rights reserved.

Subject

Infants, Pneumònia, Moçambic

Subject (English)

Children, Pneumonia, Mozambique

Citation

Collections

Articles publicats en revistes (ISGlobal)

Citation

BASSAT ORELLANA, Quique, et al. Hypoxaemia in Mozambican children < 5 years of age admitted
                to hospital with clinical severe pneumonia: clinical features
                and performance of predictor models. Tropical Medicine & International Health. 2016. ISSN 1360-2276. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/100564

Export metadata

JSON - METS

Share record