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PAYTUBÍ CENDRÓS ALBERT.pdf (1.74 MB)

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Document embargat fins el 2026-09-04

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Treball de fi de grau

Data de publicació

2024-06

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cc-by-nc-nd (c) Paytubí, 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/215053

Synthesis and characterization of new HIV-1 antiviral agents

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HIV is a virus that, unfortunately, has spread throughout planet Earth. This virus causes a disease called AIDS, acquired immunodeficiency syndrome. Currently, there is no cure for this virus, but there are treatments that allow HIV-positive people to live with it. For this reason, new treatments are being sought to completely eradicate HIV. In this project, a new antiviral agent against HIV has been synthesized on a large scale and fully characterized by 1H and 13C NMR and mass spectrometry. This new antiviral agent is based on a terphenyl structure containing three benzene rings linked by single bonds and functionalized with aliphatic chains terminated with guanidinium groups. The new antiviral agent was designed to mimic a secondary structure of the Rev protein and, consequently, block the RRE-Rev complex and stop HIV replication

Descripció

Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2024, Tutor: Vicente Marchán Sancho

Matèries

Síntesi orgànica, VIH (Virus), Medicaments antivírics, Treballs de fi de grau

Matèries (anglès)

Organic synthesis, HIV (Viruses), Antiviral agents, Bachelor's theses

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Treballs Finals de Grau (TFG) - Química

Citació

PAYTUBÍ CENDRÓS, Albert. Synthesis and characterization of new HIV-1 antiviral agents. [consulta: 23 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/215053]

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