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Issues in the Differential Diagnosis of Uterine Low-grade Endometrioid Carcinoma, Including Mixed Endometrial Carcinomas: Recommendations from the International Society of Gynecological Pathologists
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This article provides practical recommendations developed from the International Society of Gynecological Pathologists Endometrial Carcinoma Project to address 4 issues that may arise in the diagnosis of uterine corpus low-grade endometrioid carcinoma: (1) The distinction between atypical hyperplasia and low-grade endometrioid carcinoma. (2) The distinction between low-grade endometrioid carcinoma and serous carcinoma. (3) The distinction between corded and hyalinized or spindle cell variants of low-grade endometrioid carcinoma and carcinosarcoma. (4) The diagnostic criteria for mixed endometrial carcinomas, a rare entity that should be diagnosed only after exclusion of a spectrum of tumors including morphologic variants of endometrioid carcinoma, dedifferentiated endometrial carcinoma, carcinosarcoma, and endometrial carcinomas with ambiguous morphology.
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RABBAN, Joseph t., GILKS, C. blake, MALPICA, Anais, MATIAS-GUIU, Xavier, MITTAL, Khush, MUTTER, George l., OLIVA, Esther, PARKASH, Vinita, RONNETT, Brigitte m., STAATS, Paul, STEWART, Colin j. r., MCCLUGGAGE, W. glenn. Issues in the Differential Diagnosis of Uterine Low-grade Endometrioid Carcinoma, Including Mixed Endometrial Carcinomas: Recommendations from the International Society of Gynecological Pathologists. _International Journal of Gynecological Pathology_. 2019. Vol. 38, núm. 1, pàgs. S25-S39. [consulta: 23 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/171643]