Avui, dijous 7 de maig, el Dipòsit Digital no estarà operatiu per tasques d'actualització. Disculpeu les molèsties.
Hoy, jueves 7 de mayo, el Dipòsit Digital no estará operativo debido a tareas de actualización. Disculpen las molestias.
Today, Thursday, May 7th, the Digital Repository will be unavailable due to a system update.

Fitxers

2020_AdvIntSys_Engineering_SanchezS.pdf (23.86 MB)

Tipus de document

Altres

Versió

Versió publicada

Data de publicació

2020-07-21

Llicència de publicació

cc by (c) Van Moolenbroek, Guido T. et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/191782

Engineering Intelligent Nanosystems for Enhanced Medical Imaging

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1002/aisy.202000087

Resum

Medical imaging serves to obtain anatomical and physiological data, supporting medical diagnostics as well as providing therapeutic evaluation and guidance. A variety of contrast agents have been developed to enhance the recorded signals and to provide molecular imaging. However, fast clearance from the body or nonspecific biodistribution often limit their efficiency, constituting challenges that need to be overcome. Nanoparticle-based systems are currently emerging as versatile and highly integrated platforms providing improved circulating times, tissue specificity, high loading capacity for signaling moieties, and multimodal imaging features. Furthermore, nanoengineered devices can be tuned for specific applications and the development of responsive behaviors. Responses include in situ modulation of nanoparticle size, increased intratissue mobility through active propulsion of motorized particles, and active modulation of the particle surroundings such as the extracellular matrix for an improved penetration and retention at the desired locations. Once accumulated in the targeted tissue, smart nanoparticle-based contrast agents can provide molecular sensing of biomarkers or characteristics of the tissue microenvironment. In this case, the signal or contrast provided by the nanosystem is responsive to the presence or concentration of an analyte. Herein, recent developments of intelligent nanosystems to improve medical imaging are presented.

Matèries

Nanopartícules, Tomografia per emissió de positrons

Matèries (anglès)

Nanoparticles, Positron emission tomography

Citació

Col·leccions

Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))

Citació

MOOLENBROEK, Guido T. van, et al. Engineering Intelligent Nanosystems for Enhanced Medical Imaging. Advanced Intelligent Systems. 2020. Vol. 2, núm. 10. ISSN 2640-4567. [consulta: 8 de maig de 2026]. Disponible a: https://hdl.handle.net/2445/191782

Exportar metadades

JSON - METS

Compartir registre