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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/214169
Hemodynamic management of cardiogenic shock in the intensive care unit
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Abstract
Hemodynamic derangements are defining features of cardiogenic shock. Randomized clinical trials have examined the efficacy of various therapeutic interventions, from percutaneous coronary intervention to inotropes and mechanical circulatory support (MCS). However, hemodynamic management in cardiogenic shock has not been well-studied. This State-of-the-Art review will provide a framework for hemodynamic management in cardiogenic shock, including a description of the 4 therapeutic phases from initial 'Rescue' to 'Optimization', 'Stabilization' and 'de-Escalation or Exit therapy' (RO-S-E), phenotyping and phenotype-guided tailoring of pharmacological and MCS support, to achieve hemodynamic and therapeutic goals. Finally, the premises that form the basis for clinical management and the hypotheses for randomized controlled trials will be discussed, with a view to the future direction of cardiogenic shock. (c) 2024 The Authors. Published by Elsevier Inc. on behalf of International Society for Heart and Lung Transplantation. This is an open access article under the CC BY license (http://creativecommons.org/ licenses/by/4.0/).
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LIM, Hoong Sern, et al. Hemodynamic management of cardiogenic shock in the intensive care unit. The Journal of Heart and Lung Transplantation. 2024. Vol. 43, num. 7, pags. 1059-1073. ISSN 1557-3117. [consulted: 7 of June of 2026]. Available at: https://hdl.handle.net/2445/214169