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2008-05

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/126418

Mice with Pulmonary Tuberculosis Treated with Mycobacterium vaccae Develop Strikingly Enhanced Recall Gamma Interferon Responses to M. vaccae Cell Wall Skeleton

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https://doi.org/10.1128/CVI.00477-07

Abstract

Whole heat-killed Mycobacterium vaccae is used as an immunotherapeutic agent in tuberculosis (TB), but the compound(s) that triggers its immunostimulatory ability is not known. Here, we show that among different subcellular fractions, the cell wall skeleton induced a prominent expression of gamma interferon in splenocytes from both non-TB and TB M. vaccae-treated mice.

Subject

Mycobacterium tuberculosis, Ratolins (Animals de laboratori)

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Mice (Laboratory animals)

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citation

RODRÍGUEZ GÜELL, Elisabeth, et al. Mice with Pulmonary Tuberculosis Treated with Mycobacterium vaccae
Develop Strikingly Enhanced Recall Gamma Interferon Responses
to M. vaccae Cell Wall Skeleton. Clinical and Vaccine Immunology. 2008. Vol. 15, num. 5, pags. 893-896. [consulted: 18 of June of 2026]. Available at: https://hdl.handle.net/2445/126418

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