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2024-12-01

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cc-by-nc-nd (c) Hogg, B. et al., 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/217100

EMDR therapy vs. supportive therapy as adjunctive treatment in trauma-exposed bipolar patients: A randomised controlled trial

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https://doi.org/10.1016/j.sjpmh.2023.11.005

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Introduction. Patients with Bipolar Disorder (BD) are frequently exposed to traumatic events which worsen disease course, but this study is the first multicentre randomised controlled trial to test the efficacy of a trauma-focused adjunctive psychotherapy in reducing BD affective relapse rates. Materials and Methods. This multicentre randomised controlled trial included 77 patients with BD and current trauma-related symptoms. Participants were randomised to either 20 sessions of traumafocused Eye Movement Desensitization and Reprocessing (EMDR) therapy for BD, or 20 sessions of supportive therapy (ST). The primary outcome was relapse rates over 24-months, and secondary outcomes were improvements in affective and trauma symptoms, general functioning, and cognitive impairment, assessed at baseline, post-treatment, and at 12- and 24-month follow-up. The trial was registered prior to starting enrolment in clinical trials (NCT02634372) and carried out in accordance with CONSORT guidelines. Results. There was no significant difference between treatment conditions in terms of relapse rates either with or without hospitalization. EMDR was significantly superior to ST at the 12-month follow up in terms of reducing depressive symptoms (p=0.0006, d=0.969), manic symptoms (p=0.027, d=0.513), and improving functioning (p=0.038, d=0.486). There was no significant difference in dropout between treatment arms. Conclusions. Although the primary efficacy criterion was not met in the current study, trauma-focused EMDR was superior to ST in reducing of affective symptoms and improvement of functioning, with benefits maintained at six months following the end of treatment. Both EMDR and ST reduced trauma symptoms as compared to baseline, possibly due to a shared benefit of psychotherapy. Importantly, focusing on traumatic events did not increase relapses or dropouts, suggesting psychological trauma can safely be addressed in a BD population using this protocol. 

Matèries

Persones de mitjana edat, Psicoteràpia, Trastorn bipolar, Traumes psíquics, Assaigs clínics

Matèries (anglès)

Middle aged persons, Psychotherapy, Manic-depressive illness, Psychic trauma, Clinical trials

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Articles publicats en revistes (Medicina)

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HOGG, Bridget, RADUA, Joaquim, GARDOKI SOUTO, Itxaso, FONTANA MCNALLY, Marta, LUPO, Walter, REINARES, María, JIMÉNEZ MARTÍNEZ, Esther, MADRE, Mercè, BLANCO PRESAS, Laura, CORTIZO, Romina, MASSÓ RODRIGUEZ, Anna, CASTAÑO, Juan, ARGILA PLAZA, Isabel, CASTRO RODRÍGUEZ, José ignacio, COMES, Mercè, MACIAS, Cristina, SÁNCHEZ GONZÁLEZ, Roberto, MUR MILÀ, Estanislao, NOVO, Patricia, ROSA, Adriane ribeiro, VIETA I PASCUAL, Eduard, PADBERG, Frank, PÉREZ SOLÀ, Víctor, VALIENTE GÓMEZ, Alicia, MORENO ALCÁZAR, Ana, AMANN, Benedikt l.. EMDR therapy vs. supportive therapy as adjunctive treatment in trauma-exposed bipolar patients: A randomised controlled trial. _2024_. vol. 17. Vol. 4, núm. 203-214. [consulta: 11 de abril de 2026]. ISSN: 2950-2853. [Disponible a: https://hdl.handle.net/2445/217100]

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