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cc by-nc-nd (c) Martínez Segura, Albert, 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/221350

Regioselective cycloruthenation of N-(benzylidene)benzylamines: Enantiopure catalysts for transfer hydrogenation

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The reaction between N-(benzylidene)benzylamines (p-RC6H4CH=NCH2C6H5; R = Cl, H, NO2, F, OMe), [RuCl2(η6-p-cymene)]2 and potassium acetate has cleanly furnished the corresponding cycloruthenated complexes C1–C5. The process is completely regioselective, with the formation in all cases of the endo-derivative, independently of the substituent of the aromatic ring. The five-membered endo-metallacycles C6 and C7 can also be obtained from the enantiopure imines (RC)-p-RC6H4CH=NCHMeC10H7 (R = Cl, H, respectively) working under similar conditions. The crystal structures of the seven metallated compounds have been determined by X-ray diffraction. These complexes are active as catalyst precursors for the reduction of acetophenone and benzophenone by transfer hydrogenation. An enantiomeric excess of up to 77% at room temperature has been obtained with the complex C7 in the reduction of acetophenone.

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MARTÍNEZ SEGURA, Albert, EUSAMIO, Javier, MEDINA, Yaiza m., ARIZ, Katherine, GUTIÉRREZ I CURRIUS, Albert, ALBERT MACH, Joan, GRANELL SANVICENTE, Jaime ramón, FONT BARDIA, Ma. mercedes, GRABULOSA, Arnald. Regioselective cycloruthenation of N-(benzylidene)benzylamines: Enantiopure catalysts for transfer hydrogenation. _Applied Organometallic Chemistry_. 2023. Vol. 2023, núm. e7115. [consulta: 25 de febrer de 2026]. ISSN: 0268-2605. [Disponible a: https://hdl.handle.net/2445/221350]

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