Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/196042
Functional brain connectivity prior to the COVID-19 outbreak moderates the effects of coping and perceived stress on mental health changes. A first year of COVID-19 pandemic follow-up study.
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Background: The COVID-19 pandemic provides a unique opportunity to investigate the psychological impact of a global major adverse situation. Our aim was to examine, in a longitudinal prospective study, the demographic, psychological, and neurobiological factors associated with interindividual differences in resilience to the mental health impact of the pandemic. Methods: We included 2023 healthy participants (age: 54.32 ± 7.18 years, 65.69% female) from the Barcelona Brain Health Initiative cohort. A linear mixed model was used to characterize the change in anxiety and depression symptoms based on data collected both pre-pandemic and during the pandemic. During the pandemic, psychological variables assessing individual differences in perceived stress and coping strategies were obtained. In addition, in a subsample (n = 433, age 53.02 ± 7.04 years, 46.88% female) with pre-pandemic resting-state functional magnetic resonance imaging available, the system segregation of networks was calculated. Multivariate linear models were fitted to test associations between COVID-19-related changes in mental health and demographics, psychological features, and brain network status. Results: The whole sample showed a general increase in anxiety and depressive symptoms after the pandemic onset, and both age and sex were independent predictors. Coping strategies attenuated the impact of perceived stress on mental health. The system segregation of the frontoparietal control and default mode networks were found to modulate the impact of perceived stress on mental health. Conclusions: Preventive strategies targeting the promotion of mental health at the individual level during similar adverse events in the future should consider intervening on sociodemographic and psychological factors as well as their interplay with neurobiological substrates.
Matèries
Matèries (anglès)
Citació
Citació
CABELLO TOSCANO, María del rocío, VAQUÉ ALCÁZAR, Lídia, CATTANEO, Gabriele, SOLANA SÁNCHEZ, Javier, BAYES MARIN, Ivet, ABELLANEDA PÉREZ, Kilian, MACIÀ BROS, Dídac, MULET PONS, Lídia, PORTELLANO ORTIZ, Cristina, FULLANA RIVAS, Miguel àngel, OLEAGA ZUFIRÍA, Laura, GONZÁLEZ, Sofía, BARGALLÓ ALABART, Núria, TORMOS, José maría, PASCUAL LEONE, Álvaro, BARTRÉS FAZ, David. Functional brain connectivity prior to the COVID-19 outbreak moderates the effects of coping and perceived stress on mental health changes. A first year of COVID-19 pandemic follow-up study.. _Biological Psychiatry: Cognitive Neuroscience and Neuroimaging_. 2022. Vol. 8, núm. 2, pàgs. 200-209. [consulta: 28 de gener de 2026]. ISSN: 2451-9022. [Disponible a: https://hdl.handle.net/2445/196042]