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cc-by-nc (c) Ortiz-Maldonado, Valentín et al., 2021
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/193208

Factors associated with the clinical outcome of patients with relapsed/refractory CD19+acute lymphoblastic leukemia treated with ARI-0001 CART19-cell therapy

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The prognosis of patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) remains poor, particularly for those relapsing after allogeneic hema-topoietic cell transplantation (alloHCT). Novel agents such as inotuzumab ozogamicin or blinatumomab achieve increased response rates, but these are generally transient unless followed by alloHCT. Chimeric antigen receptors (CAR) targeting CD19 have shown promising results in R/R ALL, and one of these products (tisagenlecleucel) has been approved for the treatment of patients with R/R ALL up to 25 years of age.

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ORTIZ-MALDONADO GIBSON, Valentín, RIVES SOLÀ, Susana, ESPAÑOL REGO, Marta, ALONSO SALADRIGUES, A., MONTORO, Mercedes, MAGNANO, Laura, GINÉ SOCA, Eva, PASCAL I CAPDEVILA, Mariona, DÍAZ BEYÀ, Marina, CASTELLÀ CASTELLÀ, Maria, CATALÀ, Albert, FAURA, Anna, RODRÍGUEZ LOBATO, Luis gerardo, OLIVER CALDÉS, Aina, MARTÍNEZ ROCA, Alexandra, ROVIRA, Montserrat, GONZÁLEZ NAVARRO, Europa azucena, ORTEGA, Juan ramón, CID VIDAL, Joan, LOZANO, Miquel, GARCÍA REY, Enric, FERNÁNDEZ, Sara (fernández garcía), CASTRO REBOLLO, Pedro, JORDÁN GARCÍA, Iolanda, VILLAMOR I CASAS, Neus, AYMERICH GREGORIO, Marta, TORREBADELL BURRIEL, Montserrat, DEYÁ, Angela, FERNÁNDEZ DE LARREA RODRÍGUEZ, Carlos josé, BENÍTEZ-RIBAS, Daniel, TRIAS, Esteve, VAREA, Sara, CALVO ROJAS, Gonzalo, ESTEVE REYNER, Jordi, URBANO ISPIZUA, Álvaro, JUAN, Manel, DELGADO, Julio (delgado gonzález). Factors associated with the clinical outcome of patients with relapsed/refractory CD19+acute lymphoblastic leukemia treated with ARI-0001 CART19-cell therapy. _Journal for ImmunoTherapy of Cancer _. 2021. Vol. 9, núm. 12, pàgs. e003644. [consulta: 24 de gener de 2026]. ISSN: 2051-1426. [Disponible a: https://hdl.handle.net/2445/193208]

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