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Published version

Publication date

2020-02-05

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cc by (c) Yakneen et al., 2020
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/172342

Butler enables rapid cloud-based analysis of thousands of human genomes

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https://doi.org/10.1038/s41587-019-0360-3

Abstract

We present Butler, a computational tool that facilitates large-scale genomic analyses on public and academic clouds. Butler includes innovative anomaly detection and self-healing functions that improve the efficiency of data processing and analysis by 43% compared with current approaches. Butler enabled processing of a 725-terabyte cancer genome dataset from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project in a time-efficient and uniform manner.

Subject

Genoma humà, Biologia computacional

Subject (English)

Human genome, Computational biology

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Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

Citation

PCAWG Technical Working Group, PCAWG Consortium and GELPÍ BUCHACA, Josep Lluís. Butler enables rapid cloud-based analysis of thousands of human genomes. Nature Biotechnology. 2020. Vol. 38, num. 288-292. ISSN 1087-0156. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/172342

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