Butler enables rapid cloud-based analysis of thousands of human genomes

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dc.contributor.authorPCAWG Technical Working Group
dc.contributor.authorPCAWG Consortium
dc.contributor.authorGelpí Buchaca, Josep Lluís
dc.date.accessioned2020-11-26T12:38:38Z
dc.date.available2020-11-26T12:38:38Z
dc.date.issued2020-02-05
dc.date.updated2020-11-26T12:38:38Z
dc.description.abstractWe present Butler, a computational tool that facilitates large-scale genomic analyses on public and academic clouds. Butler includes innovative anomaly detection and self-healing functions that improve the efficiency of data processing and analysis by 43% compared with current approaches. Butler enabled processing of a 725-terabyte cancer genome dataset from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project in a time-efficient and uniform manner.
dc.format.extent5 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec695947
dc.identifier.issn1087-0156
dc.identifier.pmid32024987
dc.identifier.urihttps://hdl.handle.net/2445/172342
dc.language.isoeng
dc.publisherNature Publishing Group
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1038/s41587-019-0360-3
dc.relation.ispartofNature Biotechnology, 2020, vol. 38, p. 288-292
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/739563/EU//EOSCpilot
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/336045/EU//CHROMOTHRIPSIS
dc.relation.urihttps://doi.org/10.1038/s41587-019-0360-3
dc.rightscc by (c) Yakneen et al., 2020
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/
dc.sourceArticles publicats en revistes (Bioquímica i Biomedicina Molecular)
dc.subject.classificationGenoma humà
dc.subject.classificationBiologia computacional
dc.subject.otherHuman genome
dc.subject.otherComputational biology
dc.titleButler enables rapid cloud-based analysis of thousands of human genomes
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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