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cc by-nc (c) Giménez Milà et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/173785

Impact of surgical technique and analgesia on clinical outcomes after lung transplantation A STROBE-compliant cohort study

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There is paucity of data on the impact of surgical incision and analgesia on relevant outcomes. A retrospective STROBE-compliant cohort study was performed between July 2007 and August 2017 of patients undergoing lung transplantation. Gender, age, indication for lung transplantation, and the 3 types of surgical access (Thoracotomy (T), Sternotomy (S), and Clamshell (C)) were used, as well as 2 analgesic techniques: epidural and intravenous opioids. Outcome variables were: pain scores; postoperative hemorrhage in the first 24 hours, duration of mechanical ventilation, and length of stay at intensive care unit (ICU). Three hundred forty-one patients were identified. Thoracotomy was associated with higher pain scores than Sternotomy (OR 1.66, 95% CI: 1.01; 2.74, P: .045) and no differences were found between Clamshell and Sternotomy incision. The median blood loss was 800 mL [interquartile range (IQR): 500; 1238], thoracotomy patients had 500 mL [325; 818] (P < .001). Median durations of mechanical ventilation in Thoracotomy, Sternotomy, and Clamshell groups were 19 [11; 37] hours, 34 [IQR 16; 57.5] hours, and 27 [IQR 15; 50.5] hours respectively. Thoracotomy group were discharged earlier from ICU (P < .001). Thoracotomy access produces less postoperative hemorrhage, duration of mechanical ventilation, and lower length of stay in ICU, but higher pain scores and need for epidural analgesia.

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GIMÉNEZ MILÀ, Marc, VIDELA, Sebastià, PALLARÈS, Natàlia, SABATÉ PES, Antoni, PARMAR, Jasvir, CATARINO, Pedro, TOSH, Will, RAFIQ, Muhammad uma, NALPON, Jacinta, VALCHANOV, Kamen. Impact of surgical technique and analgesia on clinical outcomes after lung transplantation A STROBE-compliant cohort study. _Medicine_. 2020 vol. 99. Vol. 46. [consulta: 28 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/173785]

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