Organizing pneumonia in a patient with hodgkin's lymphoma and large B cell lymphoma: a rare association

Abstract

Organizing Pneumonia (OP) is classified as an Idiopathic Interstitial Pneumonia (IIP).1 Clinically, the patients present dyspnea, cough, and low fever, and usually respond well to corticosteroids, reaching clinical and radiologic resolution in a short timeframe. However, sometimes infiltrates do recur and may not resolve. Radiologically, migratory consolidations are identified in high-resolution computed tomography (HRCT), sometimes associated with progressive fibrosis with reticulation and areas of persistent consolidation.1 The histology reveals “proliferation of fibroblastic tissue within small airways, alveolar ducts, and alveolar spaces”.2 OP can be secondary to other pathologies such as common variable immunodeficiency3 and malignant disease among others.4 At times no etiology is identified and the term Cryptogenic Organizing Pneumonia (COP) is used.1 Furthermore, OP could coexist or mimic a malignant disease.4,5