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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/128863
Acute flaccid paralysis (AFP) surveillance: challenges and opportunities from 18 years' experience, Spain, 1998 to 2015
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Acute flaccid paralysis (AFP) surveillance is key for global polio eradication. It allows detecting poliovirus (PV) reintroductions from endemic countries. This study describes AFP surveillance in Spain from 1998 to 2015. During this time, 678 AFP cases were reported to the Spanish National Surveillance Network. The mean notification rate was 0.58 AFP cases/100,000 population under 15 years old (range: 0.45/100,000-0.78/100,000). Two periods (P) are described: P1 (1998-2006) with the AFP notification rate ranging from 0.66/100,000 to 0.78/100,000, peaking in 2001 (0.84/100,000); and P2 (2007-2015) when the AFP rate ranged from 0.43/100,000 to 0.57/100,000, with the lowest rate in 2009 (0.31/100,000). No poliomyelitis cases were caused by wild PV infections, although two Sabin-like PVs and one imported vaccine-derived PV-2 were detected. Overall, 23 (3.4%) cases met the hot case definition. Most cases were clinically diagnosed with Guillain-Barré syndrome (76.9%; 504/655). The adequate stool collection rate ranged from 33.3% (7/21) to 72.5% (29/40). The annual proportion of AFP cases with non-polio enterovirus findings varied widely across the study period. AFP surveillance with laboratory testing for non-polio enteroviruses must be maintained and enhanced both to monitor polio eradication and to establish sensitive surveillance for prompt detection of other enteroviruses causing serious symptoms.
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MASA CALLES, Josefa, TORNER GRÀCIA, Núria, LÓPEZ PEREA, Noemí, TORRES DE MIER, María v., FERNÁNDEZ MARTÍNEZ, Beatriz, CABRERIZO, María, GALLARDO GARCÍA, Virtudes, MALO, Carmen, MARGOLLES, Mario, PORTELL, Margarita, ABADÍA, Natividad, BLASCO, Aniceto, GARCÍA HERNÁNDEZ, Sara, MARCOS, Henar, RABELLA, Núria, MARÍN, Celia, FUENTES, Amelia, LOSADA, Isabel, GARCÍA GUTIÉRREZ, Juan, NIETO, Alba, GARCÍA ORTÚZAR, Visitación, GARCÍA CENOZ, Manuel, ARTEAGOITIA, José maría, BLANCO MARTÍNEZ, Ángela, RIVAS, Ana, CASTRILLEJO, Daniel, Spanish Afp Surveillance Working Group. Acute flaccid paralysis (AFP) surveillance: challenges and opportunities from 18 years' experience, Spain, 1998 to 2015. _Eurosurveillance_. 2018. Vol. 23, núm. 47. [consulta: 20 de gener de 2026]. ISSN: 1560-7917. [Disponible a: https://hdl.handle.net/2445/128863]