Reactive perforating collagenosis successfully treated with dupilumab

Abstract

A woman in her 40s with a history of atopic dermatitis in her childhood and no other medical history consulted with a disseminated, pruritic, papulonodular eruption of 7 months of duration. On examination, the patient had multiple papules and nodules with a crateriform appearance, an erythematous border and a large central necrotic crust, affecting the trunk, arms and legs. There was no palmar-plantar nor mucosal involvement.