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Ferrerira_E_Pathogens_2020.pdf (1.65 MB)

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2020

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cc by (c) Ferreira Monteiro, Eliana et al, 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/182968

Naturally Acquired Humoral Immunity against Malaria Parasites in Non-Human Primates from the Brazilian Amazon, Cerrado and Atlantic Forest.

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http://dx.doi.org/ 10.3390/pathogens9070525

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Plasmodium - Plasmodium brasilianum - P. malariae - P. malariae - P. falciparum - P. vivax - Plasmodium content: - "Non-human primates (NHPs) have been shown to be infected by parasites of the genus " - ", the etiological agent of malaria in humans, creating potential risks of zoonotic transmission. " - ", a parasite species similar to " - " of humans, have been described in NHPs from Central and South America, including Brazil. The merozoite surface protein 1 (MSP1), besides being a malaria vaccine candidate, is highly immunogenic. Due to such properties, we tested this protein for the diagnosis of parasite infection. We used recombinant proteins of " - " MSP1, as well as of " - " and " - ", for the detection of antibodies anti-MSP1 of these parasite species, in the sera of NHPs collected in different regions of Brazil. About 40% of the NHP sera were confirmed as reactive to the proteins of one or more parasite species. A relatively higher number of reactive sera was found in animals from the Atlantic Forest than those from the Amazon region, possibly reflecting the former more intense parasite circulation among NHPs due to their proximity to humans at a higher populational density. The presence of " - " positive NHPs in the surveyed areas, being therefore potential parasite reservoirs, needs to be considered in any malaria surveillance program."

Matèries

Malària, Immunitat

Matèries (anglès)

Malaria, Immunity

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Articles publicats en revistes (ISGlobal)

Citació

FERREIRA MONTEIRO, Eliana, FERNÁNDEZ BECERRA, Carmen, SILVA ARAUJO, Maisa da, REZENDE MESSIAS, Mariluce, SHOZO OZAKI, Luis, RIBEIRO DE CASTRO DUARTE, Ana maria, GALVAO BUENO, Marina, CATAO DIAS, Jose luiz, ROMEIRO FERNANDES CHAGAS, Carolina, SILVA MATHIAS, Bruno da, GOMES DOS SANTOS, Mayra, SANTOS, Stéfanie vanessa, MOREIRA HOLCMAN, Marcia, SOUZA, Julio cesar de jr., KIRCHGATTER, Karin. Naturally Acquired Humoral Immunity against Malaria Parasites
in Non-Human Primates from the Brazilian Amazon, Cerrado and
Atlantic Forest.. _Pathogens_. 2020. Vol.  vol 9, núm. num 7. [consulta: 21 de gener de 2026]. ISSN: 2076-0817. [Disponible a: https://hdl.handle.net/2445/182968]

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