Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/176037
The direct and indirect effects of COVID‐19 pandemic in a real‐life hematological setting
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Background: Clinical outcomes of novel coronavirus 2019 disease (COVID-19) in onco-hematological patients are unknown. When compared to non-immunocompromised patients, onco-hematological patients seem to have higher mortality rates. Aims: We describe the characteristics and outcomes of a consecutive cohort of 24 onco-hematological patients with COVID-19 during the first month of the pandemic. We also describe variations in healthcare resource utilization within our hematology department. Methods and results: Data from patients between the first month of the pandemic were retrospectively collected. Clinical and logistic data were also collected and compared with the average values from the prior 3 months of activity. Prevalence of COVID-19 in our hematological population was 0.4%. Baseline characteristics were as follows: male sex: 83%, lymphoid diseases: 46%, median age: 69 (22-82) years. Median follow-up in survivors was 14 (9-28) days and inpatient mortality rate was 46%. Average time to moderate/severe respiratory insufficiency and death were 3 (1-10) and 10 (3-18) days, respectively. Only 1 out of every 12 patients who developed moderate to severe respiratory insufficiency recovered. Upon univariate analysis, the following factors were associated with higher mortality: age ≥ 70 years (P = .01) and D-dimer ≥900 mcg/L (P = .04). With respect to indirect effects during the COVID-19 pandemic, and when compared with the prior 3 months of activity, inpatient mortality (excluding patients with COVID-19 included in the study) increased by 56%. This was associated with a more frequent use of vasoactive drugs (+300%) and advanced respiratory support (+133%) in the hematology ward. In the outpatient setting, there was a reduction in initial visits (-55%) and chemotherapy sessions (-19%). A significant increase in phone visits was reported (+581%). Conclusion: COVID-19 pandemic is associated with elevated mortality in hematological patients. Negative indirect effects are also evident within this setting.
Matèries
Matèries (anglès)
Citació
Citació
CONDOM, Maria, MUSSETTI, Alberto, MALUQUER, Clara, PARODY, Rocío, GONZÁLEZ BARCA, Eva, ARNAN, Montserrat, ALBASANZ PUIG, Adaia, POMARES, Helena, SALAS, Maria queralt, CARRO, Itziar, PEÑA, Marta, CLAPES, Victòria, BACA CANO, Cristina, OLIVEIRA RAMOS, Ana carla, SANZ LINARES, Gabriela, MORENO GONZÁLEZ, Gabriel, MERCADAL, Santiago, BOQUÉ GENOVARD, Concepción, GUDIOL GONZÁLEZ, Carlota, DOMINGO DOMÈNECH, Eva, SUREDA, Anna. The direct and indirect effects of COVID‐19 pandemic in a real‐life hematological setting. _Cancer Reports_. 2021. [consulta: 23 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/176037]