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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/118849
Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery
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Brain delivery is one of the major challenges in drug development because of the high number of patients suffering from neural diseases and the low efficiency of the treatments available. Although the blood-brain barrier (BBB) prevents most drugs from reaching their targets, molecular vectors - known as BBB shuttles - offer great promise to safely overcome this formidable obstacle. In recent years, peptide shuttles have received growing attention because of their lower cost, reduced immunogenicity, and higher chemical versatility than traditional Trojan horse antibodies and other proteins.
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OLLER SALVIA, Benjamí, et al. Blood-brain barrier shuttle peptides: an emerging paradigm for brain delivery. Chemical Society Reviews. 2016. Vol. 45, num. 17, pags. 4690-4707. ISSN 0306-0012. [consulted: 9 of August of 2026]. Available at: https://hdl.handle.net/2445/118849