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Zebrafish as a model for developmental toxicity assessment
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The zebrafish embryo has emerged as promising
alternative
model for traditional in vivo developmental toxicological
screening due to their advantageous characteristics as their small size
and transparency. In this paper, we reviewed the applicability of the
zebrafish embryo model in some relevant areas to human t
oxicology
as developmental toxicity, cardiovascular toxicity and neurotoxicity
(behavioral assessment). Despite the promising results, further
optimization and testing of more substances as well as a harmonized
methodology is needed to streamline the metho
ds and make the assay
conducive to medium
-
throughput.
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Podeu consultar el llibre complet a: http://hdl.handle.net/2445/67430
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TEIXIDÓ CONDOMINES, Elisabet, et al. Zebrafish as a model for developmental toxicity assessment. Recent Advances in Pharmaceutical Sciences V. 2015. Vol. Editors: Diego Muñoz Torrero, num. Pilar Vinardell & Javier Palazón, pags. 65-83. [consulted: 1 of July of 2026]. Available at: https://hdl.handle.net/2445/67544