Carregant...
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/198370
High-throughput biointerfaces for direct, label-free, and multiplexed metaplasmonic biosensing
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
In recent years, metaplasmonic biosensors have emerged as a novel counterpart of well-established plasmonic biosensors based on thin metallic layers. Metaplasmonic biosensors offer high potential for sensor miniaturiza-tion, extreme sensitivity biosensing, and high multiplexing capabilities with detection methods free of coupling optical elements. These capabilities make metaplasmonic biosensors highly attractive for Point-of-Care and handled/portable devices or novel On-Chip devices; as a result, it has increased the number of prototypes and potential applications that emerged during the last years. One of the main challenges to achieving fully operative devices is the achievement of high-throughput biointerfaces for sensitive and selective biodetection in complex media. Despite the superior surface sensitivity achieved by metaplasmonic sensors compared to conventional plasmonic sensors based on metallic thin films, the main limitations to achieving high-throughput and multiplexed biosensing usually are associated with the sensitivity and selectivity of the bioin-terface and, as a consequence, their application to the direct analysis of real complex samples. This graphical review discusses the potential challenges and capabilities of different biofunctionalization strategies, biorecog-nition elements, and antifouling strategies to achieve scalable and high-throughput metaplasmonic biosensing for Point-of-Care devices and bioengineering applications like Organs-On-Chip.
Matèries (anglès)
Citació
Citació
UGARTE OROZCO, Maria j., LÓPEZ MUÑOZ, Gerardo a., ANTONIO PÉREZ, Aurora, ESQUIVEL ORTIZ, Karla m., RAMON AZCON, Javier. High-throughput biointerfaces for direct, label-free, and multiplexed metaplasmonic biosensing. _Current Research In Biotechnology_. 2023. Vol. 5, núm. 100119. [consulta: 2 de febrer de 2026]. ISSN: 2590-2628. [Disponible a: https://hdl.handle.net/2445/198370]