The Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies

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dc.contributor.authorRayatpour, Atefeh
dc.contributor.authorFarhangi, Sahar
dc.contributor.authorVerdaguer Cardona, Ester
dc.contributor.authorOlloquequi, Jordi
dc.contributor.authorUreña Bares, Jesús Mariano
dc.contributor.authorAuladell i Costa, M. Carme
dc.contributor.authorJavan, Mohammad
dc.date.accessioned2022-03-11T08:45:24Z
dc.date.available2022-03-11T08:45:24Z
dc.date.issued2021-10-11
dc.date.updated2022-03-11T08:45:24Z
dc.description.abstractDespite the significant differences in pathological background of neurodegenerative diseases,epileptic seizures are a comorbidity in many disorders such as Huntington disease (HD), Alzheimer 'sdisease (AD), and multiple sclerosis (MS). Regarding the last one, specifically, it has been shownthat the risk of developing epilepsy is three to six times higher in patients with MS compared tothe general population. In this context, understanding the pathological processes underlying thisconnection will allow for the targeting of the common and shared pathological pathways involvedin both conditions, which may provide a new avenue in the management of neurological disorders.This review provides an outlook of what is known so far about the bidirectional association betweenepilepsy and MS
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec717135
dc.identifier.issn1424-8247
dc.identifier.urihttps://hdl.handle.net/2445/184034
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ph14101031
dc.relation.ispartofPharmaceuticals, 2021, vol. 14, num. 10, p. 1031
dc.relation.urihttps://doi.org/10.3390/ph14101031
dc.rightscc-by (c) Rayatpour, Atefeh et al., 2021
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Bioquímica i Fisiologia)
dc.subject.classificationMalalties neurodegeneratives
dc.subject.classificationMetabolisme cel·lular
dc.subject.otherNeurodegenerative Diseases
dc.subject.otherCell metabolism
dc.titleThe Cross Talk between Underlying Mechanisms of Multiple Sclerosis and Epilepsy May Provide New Insights for More Efficient Therapies
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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