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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/36346
An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines
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A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.
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AMAT TUSÓN, Mercedes, et al. An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines. Journal of Organic Chemistry. 2008. Vol. 73, num. 17, pags. 6920-6923. ISSN 0022-3263. [consulted: 6 of June of 2026]. Available at: https://hdl.handle.net/2445/36346