An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines

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dc.contributor.authorAmat Tusón, Mercedes
dc.contributor.authorPérez Bosch, Maria
dc.contributor.authorMinaglia, Annamaria Tania
dc.contributor.authorBosch Cartes, Joan
dc.date.accessioned2013-04-25T15:32:01Z
dc.date.available2013-04-25T15:32:01Z
dc.date.issued2008-06-13
dc.date.updated2013-04-25T15:32:01Z
dc.description.abstractA synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position.
dc.format.extent4 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec559907
dc.identifier.issn0022-3263
dc.identifier.urihttps://hdl.handle.net/2445/36346
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: http://dx.doi.org/10.1021/jo801172b
dc.relation.ispartofJournal of Organic Chemistry, 2008, vol. 73, num. 17, p. 6920-6923
dc.relation.urihttp://dx.doi.org/10.1021/jo801172b
dc.rights(c) American Chemical Society , 2008
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationCompostos organometàl·lics
dc.subject.classificationCoure
dc.subject.classificationSíntesi orgànica
dc.subject.classificationLactames
dc.subject.otherOrganometallic compounds
dc.subject.otherCopper
dc.subject.otherSynthetic organic chemistry
dc.subject.otherLactams
dc.titleAn enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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