Carregant...
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/207223
Serological autoimmune profile of systemic lupus erythematosus in deep and non-deep endometriosis patients
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Several studies have reported a high prevalence of autoimmune diseases such as systemic lupus erythematosus (SLE) in endometriosis patients. The aim of this study was to evaluate the SLE autoimmune antibody profile in patients with deep (DE) and non-deep endometriosis (Non-DE).Four groups of premenopausal patients were evaluated: patients with DE (n = 50); patients with ovarian endometriomas (Non-DE; n = 50); healthy patients without endometriosis (C group; n = 45); and SLE patients without endometriosis (SLE group; N = 46). Blood samples were obtained and the standard SLE autoimmune profile was evaluated in all patients. Pain symptoms related to endometriosis and clinical SLE manifestations were also recorded.The DE group presented a statistically significant higher proportion of patients with antinuclear antibodies (ANA) (20%) compared to the Non-DE group (4%) and C group (2.2%). Levels of complement were more frequently lower among DE and Non-DE patients although differences did not reach statistical significance. Similarly, anti-dsDNA antibodies and anticoagulant lupus were positive in more patients of the DE group but did not reach statistical significance. The DE group complained of more arthralgia and asthenia compared to the Non-DE and C groups.The results of this study showed higher positivity of ANA and greater arthralgia and asthenia in patients with DE compared with Non-DE patients and healthy controls, suggesting that they may have a higher susceptibility to autoimmune diseases and present more generalized pain.Copyright © 2023. Published by Elsevier B.V.
Matèries
Matèries (anglès)
Citació
Citació
COLOMA, José luis, MARTÍNEZ ZAMORA, María ángeles, TÀSSIES PENELLA, María dolores, REVERTER CALATAYUD, Juan carlos, ESPINOSA GARRIGA, Gerard, CERVERA I SEGURA, Ricard, CARMONA HERRERA, Francisco. Serological autoimmune profile of systemic lupus erythematosus in deep and non-deep endometriosis patients. _Journal Of Reproductive Immunology_. 2023. Vol. 156, núm. 103827. [consulta: 7 de gener de 2026]. ISSN: 0165-0378. [Disponible a: https://hdl.handle.net/2445/207223]