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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/117586

A new synthetic approach to the lactol moiety of halichoblelide

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A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from commercially available (R)-1-butyn-3-ol. The key step is the hydroboration of a chiral protected 1,2-butadien-3-ol and its addition to furfural.

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SANTOS, David, et al. A new synthetic approach to the lactol moiety of halichoblelide. Tetrahedron. 2011. Vol. 67, num. 29, pags. 5184-5188. ISSN 0040-4020. [consulted: 8 of June of 2026]. Available at: https://hdl.handle.net/2445/117586

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