Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

Files

686151.pdf (730.47 KB)

Document type

Article

Version

Accepted version

Publication date

2018-05

All rights reserved

Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/131951

The BRICS (Bronchiectasis Radiologically Indexed CT Score): A Multicenter Study Score for Use in Idiopathic and Postinfective Bronchiectasis

Journal Title

Authors

Director/Tutor

Journal ISSN

Volume Title

Related resource

https://doi.org/10.1016/j.chest.2017.11.033

Abstract

Objectives The goal of this study was to develop a simplified radiological score that could assess clinical disease severity in bronchiectasis. Methods The Bronchiectasis Radiologically Indexed CT Score (BRICS) was devised based on a multivariable analysis of the Bhalla score and its ability in predicting clinical parameters of severity. The score was then externally validated in six centers in 302 patients. Results A total of 184 high-resolution CT scans were scored for the validation cohort. In a multiple logistic regression model, disease severity markers significantly associated with the Bhalla score were percent predicted FEV1, sputum purulence, and exacerbations requiring hospital admission. Components of the Bhalla score that were significantly associated with the disease severity markers were bronchial dilatation and number of bronchopulmonary segments with emphysema. The BRICS was developed with these two parameters. The receiver operating-characteristic curve values for BRICS in the derivation cohort were 0.79 for percent predicted FEV1, 0.71 for sputum purulence, and 0.75 for hospital admissions per year; these values were 0.81, 0.70, and 0.70, respectively, in the validation cohort. Sputum free neutrophil elastase activity was significantly elevated in the group with emphysema on CT imaging. Conclusions A simplified CT scoring system can be used as an adjunct to clinical parameters to predict disease severity in patients with idiopathic and postinfective bronchiectasis.

Subject

Bronquitis, Assaigs clínics, Hospitals, Malalties de l'aparell respiratori

Subject (English)

Bronchitis, Clinical trials, Hospitals, Respiratory diseases

Citation

Collections

Articles publicats en revistes (Medicina)

Citation

BEDI, Pallavi, et al. The BRICS (Bronchiectasis Radiologically Indexed CT Score): A Multicenter Study Score for Use in Idiopathic and Postinfective Bronchiectasis. Chest. 2018. Vol. 153, num. 5, pags. 1177-1186. ISSN 0012-3692. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/131951

Export metadata

JSON - METS

Share record