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2020-01-01

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cc by (c) Moyano Rodriguez et al., 2020
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/173743

PP2A Functions during Mitosis and Cytokinesis in Yeasts

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https://doi.org/10.3390/ijms21010264

Abstract

Protein phosphorylation is a common mechanism for the regulation of cell cycle progression. The opposing functions of cell cycle kinases and phosphatases are crucial for accurate chromosome segregation and exit from mitosis. Protein phosphatases 2A are heterotrimeric complexes that play essential roles in cell growth, proliferation, and regulation of the cell cycle. Here, we review the function of the protein phosphatase 2A family as the counteracting force for the mitotic kinases. We focus on recent findings in the regulation of mitotic exit and cytokinesis by PP2A phosphatases in S. cerevisiae and other fungal species.

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Mitosi, Citoquines, Llevats

Subject (English)

Mitosis, Cytokines, Yeast

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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MOYANO RODRÍGUEZ, Yolanda and QUERALT BADIA, Ethel. PP2A Functions during Mitosis and Cytokinesis in Yeasts. International Journal of Molecular Sciences. 2020. Vol. 21, num. 1. [consulted: 7 of August of 2026]. Available at: https://hdl.handle.net/2445/173743

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