Miniatura

Fitxers

725392.pdf (1.24 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2022-08-17

Llicència de publicació

cc-by-nc-nd (c) Perellón Alfonso, Rubén et al., 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/195866

Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1016/j.heliyon.2022.e10208

Resum

Psychosocial hardships associated with the COVID-19 pandemic led many individuals to suffer adverse mental health consequences, however, others show no negative effects. We hypothesized that the electroencephalographic (EEG) response to transcranial magnetic stimulation (TMS) could serve as a toy-model of an individual's capacity to resist psychological stress, in this case linked to the COVID-19 pandemic. We analyzed data from 74 participants who underwent mental health monitoring and concurrent electroencephalography with transcranial magnetic stimulation of the left dorsolateral prefrontal cortex (L-DLPFC) and left inferior parietal lobule (L-IPL). Within the following 19 months, mental health was reassessed at three timepoints during lock-down confinement and different phases of de-escalation in Spain. Compared with participants who remained stable, those who experienced increased mental distress showed, months earlier, significantly larger late EEG responses locally after L-DLPFC stimulation (but not globally nor after L-IPL stimulation). This response, together with years of formal education, was significantly predictive of mental health status during the pandemic. These findings reveal that the effect of TMS perturbation offers a predictive toy model of psychosocial stress response, as exemplified by the COVID-19 pandemic.

Matèries

COVID-19, SARS-CoV-2, Resiliència (Tret de la personalitat), Salut mental, Escorça frontal, Electroencefalografia

Matèries (anglès)

COVID-19, SARS-CoV-2, Resilience (Personality trait), Mental health, Prefrontal cortex, Electroencephalography

Citació

Col·leccions

Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Institut de Neurociències (UBNeuro))

Citació

PERELLÓN ALFONSO, Ruben, REDONDO-CAMÓS, María, ABELLANEDA PÉREZ, Kilian, CATTANEO, Gabriele, DELGADO GALLÉN, Selma, ESPAÑA IRLA, Goretti, SOLANA SÁNCHEZ, Javier, TORMOS, José maría, PASCUAL LEONE, Álvaro, BARTRÉS FAZ, David. Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic. _Heliyon_. 2022. Vol. 8, núm. e10208. [consulta: 31 de gener de 2026]. ISSN: 2405-8440. [Disponible a: https://hdl.handle.net/2445/195866]

Exportar metadades

JSON - METS

Compartir registre