Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

Files

TFG_Román_Pobo_Claudia.pdf (776.22 KB)

Document type

Bachelor thesis

Publication date

2025-06

Publication license

cc-by-nc-nd (c) Román, 2025
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/223249

Modelling Nanoparticle-Cell Interactions: A Kinetic Approach

Journal Title

Authors

Director/Tutor

Journal ISSN

Volume Title

Related resource

Abstract

This project addresses the effect of nanoparticle functionalisation on binding affinity to endothelial brain cells. This kind of characterization is fundamental to the optimization of drug delivery to the brain, allowing for treatment of neurodegenerative diseases. For this, we perform a proof of concept binding experiment on bEnd.3 cells with ApoE-functionalized and pristine PEG-PLA polymersomes, and propose a deterministic kinetic model to describe these systems.

Description

Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2025, Tutors: Maria del Carmen Miguel López, Marco Basile, Zhendong Xie

Subject

Biofísica, Cinètica d'unió, Treballs de fi de grau

Subject (English)

Biophysics, Binding kinetics, Bachelor's theses

Citation

Collections

Treballs Finals de Grau (TFG) - Física

Citation

ROMÁN POBO, Claudia. Modelling Nanoparticle-Cell Interactions: A Kinetic Approach. [consulted: 10 of August of 2026]. Available at: https://hdl.handle.net/2445/223249

Export metadata

JSON - METS

Share record