Modelling Nanoparticle-Cell Interactions: A Kinetic Approach

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dc.contributor.advisorMiguel López, María del Carmen
dc.contributor.advisorBasile, Marco
dc.contributor.advisorXie, Zhendong
dc.contributor.authorRomán Pobo, Claudia
dc.date.accessioned2025-09-18T13:27:16Z
dc.date.available2025-09-18T13:27:16Z
dc.date.issued2025-06
dc.descriptionTreballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2025, Tutors: Maria del Carmen Miguel López, Marco Basile, Zhendong Xieca
dc.description.abstractThis project addresses the effect of nanoparticle functionalisation on binding affinity to endothelial brain cells. This kind of characterization is fundamental to the optimization of drug delivery to the brain, allowing for treatment of neurodegenerative diseases. For this, we perform a proof of concept binding experiment on bEnd.3 cells with ApoE-functionalized and pristine PEG-PLA polymersomes, and propose a deterministic kinetic model to describe these systems.ca
dc.format.extent6 p.
dc.format.mimetypeapplication/pdf
dc.identifier.urihttps://hdl.handle.net/2445/223249
dc.language.isoengca
dc.rightscc-by-nc-nd (c) Román, 2025
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceTreballs Finals de Grau (TFG) - Física
dc.subject.classificationBiofísicacat
dc.subject.classificationCinètica d'uniócat
dc.subject.classificationTreballs de fi de graucat
dc.subject.otherBiophysicseng
dc.subject.otherBinding kineticseng
dc.subject.otherBachelor's theseseng
dc.titleModelling Nanoparticle-Cell Interactions: A Kinetic Approacheng
dc.typeinfo:eu-repo/semantics/bachelorThesisca

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