Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/209561
Merging BioActuation and BioCapacitive properties: A 3D bioprinted devices to self-stimulate using self-stored energy
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
Biofabrication of three-dimensional (3D) cultures through the 3D Bioprinting technique opens new perspectives and applications of cell-laden hydrogels. However, to continue with the progress, new BioInks with specific properties must be carefully designed. In this study, we report the synthesis and 3D Bioprinting of an electroconductive BioInk made of gelatin/fibrinogen hydrogel, C2C12 mouse myoblast and 5% w/w of conductive poly (3,4-ethylenedioxythiophene) nanoparticles (PEDOT NPs). The influence of PEDOT NPs, incorporated in the cellladen BioInk, not only showed a positive effect in cells viability, differentiation and myotube functionalities, also allowed the printed constructs to behaved as BioCapacitors. Such devices were able to electrochemically store a significant amount of energy (0.5 mF/cm2), enough to self-stimulate as BioActuator, with typical contractions ranging from 27 to 38 mu N, during nearly 50 min. The biofabrication of 3D constructs with the proposed electroconductive BioInk could lead to new devices for tissue engineering, biohybrid robotics or bioelectronics.
Subject
Subject (English)
Citation
Citation
MOLINA, Brenda G., et al. Merging BioActuation and BioCapacitive properties: A 3D bioprinted devices to self-stimulate using self-stored energy. Biosensors & Bioelectronics. 2024. Vol. 251. ISSN 1873-4235. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/209561