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Direct-acting antivirals for hepatitis C virus induce a rapid clinical and biochemical remission of porphyria cutanea tarda

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Sporadic porphyria cutanea tarda (PCT) is strongly associated with hepatitis C virus (HCV) infection in our population. 1-4 Therapeutic options for PCT include phlebotomies and low-dose 4-aminoquinolines, which show high rates of disease remission. However, some patients with PCT may present frequent relapses attributable to resistance, intolerability or poor adherence to conventional treatments and/or persistence of risk factors. In 2014, we reported the first case of a patient with active PCT and HCV-HIV coinfection cured with direct antiviral agents (DAAs).5 Herein, we present a cohort of patients demonstrating rapid and persistent remission of PCT with DAA regimes administered for HCV infection.

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COMBALIA, Andrea, TO I FIGUERAS, Jordi, LAGUNO CENTENO, Montserrat, MARTÍNEZ REBOLLAR, María, AGUILERA, Paula. Direct-acting antivirals for hepatitis C virus induce a rapid clinical and biochemical remission of porphyria cutanea tarda. _British Journal of Dermatology_. 2017. Vol. 177, núm. 5, pàgs. e183-e184. [consulta: 14 de gener de 2026]. ISSN: 0007-0963. [Disponible a: https://hdl.handle.net/2445/158499]

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