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Article

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2017-03-29

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/158499

Direct-acting antivirals for hepatitis C virus induce a rapid clinical and biochemical remission of porphyria cutanea tarda

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https://doi.org/10.1111/bjd.15502

Abstract

Sporadic porphyria cutanea tarda (PCT) is strongly associated with hepatitis C virus (HCV) infection in our population. 1-4 Therapeutic options for PCT include phlebotomies and low-dose 4-aminoquinolines, which show high rates of disease remission. However, some patients with PCT may present frequent relapses attributable to resistance, intolerability or poor adherence to conventional treatments and/or persistence of risk factors. In 2014, we reported the first case of a patient with active PCT and HCV-HIV coinfection cured with direct antiviral agents (DAAs).5 Herein, we present a cohort of patients demonstrating rapid and persistent remission of PCT with DAA regimes administered for HCV infection.

Subject

Hepatitis C, Porfíria

Subject (English)

Hepatitis C, Porphyria

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

COMBALIA, Andrea, et al. Direct-acting antivirals for hepatitis C virus induce a rapid clinical and biochemical remission of porphyria cutanea tarda. British Journal of Dermatology. 2017. Vol. 177, num. 5, pags. e183-e184. ISSN 0007-0963. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/158499

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